spr-based biacore t200 biosensor Search Results


t200 system  (GE Healthcare)
95
GE Healthcare t200 system
T200 System, supplied by GE Healthcare, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/t200 system/product/GE Healthcare
Average 95 stars, based on 1 article reviews
t200 system - by Bioz Stars, 2026-03
95/100 stars
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spr-based biacore t200 instrument  (Biacore)
90
Biacore spr-based biacore t200 instrument
BPN is a competitive PTP1B inhibitor. (A) Chemical structure of BPN. (B) The Lineweaver–Burk plot for inhibition of PTP1B enzyme reaction by BPN. The experiment was performed at 37 °C and pH 7.5. BPN concentrations were 4 (◆), 8 (■) and 16 μM (▲), respectively. (C) K i determination for BPN. The plot of apparent K m versus the concentrations of BPN. BPN concentrations were 4 (◆), 8 (■) and 16 μM (▲), respectively. (D) SPR dose–response curves of BPN. The K a , K d and K D values of BPN were 4.238 × 10 3 Ms −1 , 1.406 × 10 −2 s −1 , 3.318 × 10 −6 M, respectively. K D values of BPN was obtained by fitting the data sets to 1 : 1 binding model using Biacore <t>T200</t> Evaluation Software.
Spr Based Biacore T200 Instrument, supplied by Biacore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/spr-based biacore t200 instrument/product/Biacore
Average 90 stars, based on 1 article reviews
spr-based biacore t200 instrument - by Bioz Stars, 2026-03
90/100 stars
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t200 instrument  (Danaher Inc)
86
Danaher Inc t200 instrument
BPN is a competitive PTP1B inhibitor. (A) Chemical structure of BPN. (B) The Lineweaver–Burk plot for inhibition of PTP1B enzyme reaction by BPN. The experiment was performed at 37 °C and pH 7.5. BPN concentrations were 4 (◆), 8 (■) and 16 μM (▲), respectively. (C) K i determination for BPN. The plot of apparent K m versus the concentrations of BPN. BPN concentrations were 4 (◆), 8 (■) and 16 μM (▲), respectively. (D) SPR dose–response curves of BPN. The K a , K d and K D values of BPN were 4.238 × 10 3 Ms −1 , 1.406 × 10 −2 s −1 , 3.318 × 10 −6 M, respectively. K D values of BPN was obtained by fitting the data sets to 1 : 1 binding model using Biacore <t>T200</t> Evaluation Software.
T200 Instrument, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/t200 instrument/product/Danaher Inc
Average 86 stars, based on 1 article reviews
t200 instrument - by Bioz Stars, 2026-03
86/100 stars
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surface plasmon resonance (spr)-based binding assay  (Biacore)
90
Biacore surface plasmon resonance (spr)-based binding assay
BPN is a competitive PTP1B inhibitor. (A) Chemical structure of BPN. (B) The Lineweaver–Burk plot for inhibition of PTP1B enzyme reaction by BPN. The experiment was performed at 37 °C and pH 7.5. BPN concentrations were 4 (◆), 8 (■) and 16 μM (▲), respectively. (C) K i determination for BPN. The plot of apparent K m versus the concentrations of BPN. BPN concentrations were 4 (◆), 8 (■) and 16 μM (▲), respectively. (D) SPR dose–response curves of BPN. The K a , K d and K D values of BPN were 4.238 × 10 3 Ms −1 , 1.406 × 10 −2 s −1 , 3.318 × 10 −6 M, respectively. K D values of BPN was obtained by fitting the data sets to 1 : 1 binding model using Biacore <t>T200</t> Evaluation Software.
Surface Plasmon Resonance (Spr) Based Binding Assay, supplied by Biacore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/surface plasmon resonance (spr)-based binding assay/product/Biacore
Average 90 stars, based on 1 article reviews
surface plasmon resonance (spr)-based binding assay - by Bioz Stars, 2026-03
90/100 stars
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Image Search Results


BPN is a competitive PTP1B inhibitor. (A) Chemical structure of BPN. (B) The Lineweaver–Burk plot for inhibition of PTP1B enzyme reaction by BPN. The experiment was performed at 37 °C and pH 7.5. BPN concentrations were 4 (◆), 8 (■) and 16 μM (▲), respectively. (C) K i determination for BPN. The plot of apparent K m versus the concentrations of BPN. BPN concentrations were 4 (◆), 8 (■) and 16 μM (▲), respectively. (D) SPR dose–response curves of BPN. The K a , K d and K D values of BPN were 4.238 × 10 3 Ms −1 , 1.406 × 10 −2 s −1 , 3.318 × 10 −6 M, respectively. K D values of BPN was obtained by fitting the data sets to 1 : 1 binding model using Biacore T200 Evaluation Software.

Journal: RSC Advances

Article Title: Effects of a natural PTP1B inhibitor from Rhodomela confervoides on the amelioration of fatty acid-induced insulin resistance in hepatocytes and hyperglycaemia in STZ-induced diabetic rats

doi: 10.1039/c9ra10660j

Figure Lengend Snippet: BPN is a competitive PTP1B inhibitor. (A) Chemical structure of BPN. (B) The Lineweaver–Burk plot for inhibition of PTP1B enzyme reaction by BPN. The experiment was performed at 37 °C and pH 7.5. BPN concentrations were 4 (◆), 8 (■) and 16 μM (▲), respectively. (C) K i determination for BPN. The plot of apparent K m versus the concentrations of BPN. BPN concentrations were 4 (◆), 8 (■) and 16 μM (▲), respectively. (D) SPR dose–response curves of BPN. The K a , K d and K D values of BPN were 4.238 × 10 3 Ms −1 , 1.406 × 10 −2 s −1 , 3.318 × 10 −6 M, respectively. K D values of BPN was obtained by fitting the data sets to 1 : 1 binding model using Biacore T200 Evaluation Software.

Article Snippet: The binding affinity of BPN towards PTP1B was assayed using the SPR-based Biacore T200 instrument. hPTP1B 1-321 in 10 mM sodium acetate buffer (pH 5.0) was immobilized onto CM5 sensor chips using standard amine coupling method to 10 000 response units.

Techniques: Inhibition, Binding Assay, Software